Treating Trauma Survivors with Neurofeedback: A Grounded Theory Study Based on the Practices of Experienced Mental Health Professionals

Neuroscience, the mental health field, and the concept of trauma as an underlying factor in mental and physical disorders have been inextricably linked since the inception of the mental health professions. Numerous quantitative studies have indicated that neurofeedback may be effective in ameliorating trauma symptoms; however, there is a paucity of research exploring the factors that produce those positive outcomes. The purpose of this qualitative grounded theory study was to explore the factors and processes that influence treatment outcomes when neurofeedback is used with trauma survivors. Thirty interviews were completed with ten experienced mental health and neurofeedback professionals identified through a nomination process with a snowball sampling method. For this study a wide definition of trauma was used that included traumatic brain injury, the DSM-IV-TR (2000) criteria for posttraumatic stress disorder, and the seven symptoms associated with complex trauma (Courtois, 2008; Courtois & Ford, 2009; Herman, 1992, 1997). Research results indicate that the neurofeedback practitioner is central to the treatment process, that practitioner therapeutic skills are crucial to positive neurofeedback outcomes, and that counseling and neurofeedback may effectively complement each other in trauma treatment

Minitab: the natural choice for non-specialist statisticians?

In this article, we begin by describing the teaching methods and assignment used for the Statistics course on the MSc in Operational Research and the MSc in Operational Research and Finance, and then provide a detailed discussion of why Minitab was chosen as the software package for displaying results in lectures and for teaching in computer lab sessions

Interpreting for Vocational Rehabilitation Consumers: An Emerging Specialty

This article discusses the role of an interpreter working with vocational rehabilitation consumers in an occupational context with or without a job coach. It describes the necessity of being flexible to the needs of the deaf person and the demands of the work environment. In this situation, the interpreter who takes into consideration the roles of other involved professionals will provide the most effective services to the consumer

The collaborative relationship between transport and tourism in Scottish islands: from policy to practice

Despite a ubiquitous interest, the concept of collaboration remains elusive. Regardless, the pervasiveness of discourse pertaining to it continues to infiltrate policy as public sector reform advocates for behaviour and practice driven by an ethos of “joining-up”. The interdependency of the transport-tourism relationship provides an opportunity to consider collaboration in a context where the benefits of integration can be substantial. Within island domains the reliance of tourism economies on efficient transport systems is intensified. Consequently this research presents an analysis of the scope, role and nature of collaboration between industries whose sustainability is to a large extent symbiotic and critical to local prosperity. A review of the literature demonstrates a lack of focus on research pertaining to a stakeholder perspective of the transport-tourism relationship. Within the island environment, studies on this scenario of cross-industry engagement further diminish although the argument expressing the significance of transport in tourism is vociferous. Gaps were also identified in the conceptualisation of collaboration inhibiting a universal definition and thus a comprehensive understanding. The primary research adopted a qualitative approach. Data was collected through a series of semi-structured interviews from stakeholders across transport and tourism who fulfilled pre-considered criteria. The key findings identify constraints to collaboration in the form of structural disparity while divergent industry objectives further impede practical integration. Despite this, the role of “islandness” neutralises barriers to engagement. The propensity to cultivate social capital within these boundaried geographies provides an environment naturally conducive to the creation of collaborative capacity. Consensual development of shared goals between collaborating parties manifested as intrinsic for the purpose of buy-in and commitment throughout the collaborative process. Similarly, an absence of leadership in practice resulted in highlighting the fundamental role it delivers within collaboration. The empirical findings provide both practical and theoretical contribution. Further they present policy-makers with evidence-informed suggestions to address impediments which prevent the practice of collaboration.sub_behunpub1931_ethesesunpu

Arguments for and against the use of multiple comparison control in stochastic simulation studies

Pick up any of the standard discrete-event simulation textbooks and you will find that the output analysissection includes a note on multiple comparison control (MCC). These procedures aim to mitigate theproblem of inflating the probability of making a single type I error when comparing many simulatedscenarios simultaneously. We consider the use of MCC in stochastic simulation studies and present anargument discouraging its use in the classical sense. In particular, we focus on the impracticality ofprocedures, the benefits of common random numbers and that simulation is very different from empiricalstudies where MCC has its roots. We then consider in what instances would abandoning MCC altogetherbe problematic and what alternatives are available. We present an argument for medium to largeexploratory studies to move their attention away from classical Type I errors and instead control asubtlety different quantity: the rate of false positives amongst all ‘discoveries’

The use of case studies in OR teaching

This article investigates the current use of case studies in the teaching of Operational Research (OR) in the UK: how and where they are used; how they are developed; and whether there is an interest in training this area. It is aimed at lecturers teaching OR who are using or planning to use case studies in their teaching. It may also be of interest to policy-makers who wish to know what is being done in OR. The article focuses on the results of a survey sent to lecturers of OR in higher education in the UK. These are combined with an examination of the literature on using case studies in teaching in general and a small number of specific examples of how case studies are used in OR teaching. Case studies are included in OR teaching in a variety of ways and to develop a range of skills; particularly the ability to transfer academic knowledge to real-life contexts. The article identifies that the most significant barrier to the use of case studies in OR teaching is the development of new case studies; suggestions are made to address this, including providing training and collaboration opportunities. Overall this article provides an assessment of the ways in which case studies are used in OR; the advantages and limitationsof using them; and specific examples of their use which will provide ideas to assist in improving OR teaching

Choice-Based Demand Management and Vehicle Routing in E-Fulfillment

Attended home delivery services face the challenge of providing narrow delivery time slots to ensure customer satisfaction, while keeping the significant delivery costs under control. To that end, a firm can try to influence customers when they are booking their delivery time slot so as to steer them toward choosing slots that are expected to result in cost-effective schedules. We estimate a multinomial logit customer choice model from historic booking data and demonstrate that this can be calibrated well on a genuine e-grocer data set. We propose dynamic pricing policies based on this choice model to determine which and how much incentive (discount or charge) to offer for each time slot at the time a customer intends to make a booking. A crucial role in these dynamic pricing problems is played by the delivery cost, which is also estimated dynamically. We show in a simulation study based on real data that anticipating the likely future delivery cost of an additional order in a given location can lead to significantly increased profit as compared with current industry practice

Cost, affordability and cost-effectiveness of strategies to control tuberculosis in countries with high HIV prevalence

Background: The HIV epidemic has caused a dramatic increase in tuberculosis (TB) in East and southern Africa. Several strategies have the potential to reduce the burden of TB in high HIV prevalence settings, and cost and cost-effectiveness analyses can help to prioritize them when budget constraints exist. However, published cost and cost-effectiveness studies are limited.Methods: Our objective was to compare the cost, affordability and cost-effectiveness of seven strategies for reducing the burden of TB in countries with high HIV prevalence. A compartmental difference equation model of TB and HIV and recent cost data were used to assess the costs (year 2003 US$prices) and effects (TB cases averted, deaths averted, DALYs gained) of these strategies in Kenya during the period 2004-2023.Results: The three lowest cost and most cost-effective strategies were improving TB cure rates, improving TB case detection rates, and improving both together. The incremental cost of combined improvements to case detection and cure was below US$15 million per year (7.5% of year 2000 government health expenditure); the mean cost per DALY gained of these three strategies ranged from US$18 to US$34. Antiretroviral therapy (ART) had the highest incremental costs, which by 2007 could be as large as total government health expenditures in year 2000. ART could also gain more DALYs than the other strategies, at a cost per DALY gained of around US$260 to US$530. Both the costs and effects of treatment for latent tuberculosis infection (TLTI) for HIV+ individuals were low; the cost per DALY gained ranged from about US$85 to US$370. Averting one HIV infection for less than US$250 would be as cost-effective as improving TB case detection and cure rates to WHO target levels. Conclusions: To reduce the burden of TB in high HIV prevalence settings, the immediate goal should be to increase TB case detection rates and, to the extent possible, improve TB cure rates, preferably in combination. Realising the full potential of ART will require substantial new funding and strengthening of health system capacity so that increased funding can be used effectively

Cadherin-Mediated Differential Cell Adhesion Controls Slow Muscle Cell Migration in the Developing Zebrafish Myotome

AbstractSlow-twitch muscle fibers of the zebrafish myotome undergo a unique set of morphogenetic cell movements. During embryogenesis, slow-twitch muscle derives from the adaxial cells, a layer of paraxial mesoderm that differentiates medially within the myotome, immediately adjacent to the notochord. Subsequently, slow-twitch muscle cells migrate through the entire myotome, coming to lie at its most lateral surface. Here we examine the cellular and molecular basis for slow-twitch muscle cell migration. We show that slow-twitch muscle cell morphogenesis is marked by behaviors typical of cells influenced by differential cell adhesion. Dynamic and reciprocal waves of N-cadherin and M-cadherin expression within the myotome, which correlate precisely with cell migration, generate differential adhesive environments that drive slow-twitch muscle cell migration through the myotome. Removing or altering the expression of either protein within the myotome perturbs migration. These results provide a definitive example of homophilic cell adhesion shaping cellular behavior during vertebrate development

Intragenic Dominant Suppressors of glp-1, a Gene Essential for Cell-Signaling in Caenorhabditis elegans, Support a Role for cdcl O/SWZ6/Ankyrin Motifs in GLP-1 Function

The glp-1 gene product mediates cell-cell interactions required for cell fate specification during development in Caenorhabditis elegans. To identify genes that interact with glp-1, we screened for dominant suppressors of two temperature-sensitive glp-1 alleles and recovered 18 mutations that suppress both germline and embryonic glp-1 phenotypes. These dominant suppressors are tightly linked to glp-1 and do not bypass the requirement for a distal tip cell, which is thought to be the source of a signal that is received and transduced by the GLP-1 protein. Using single-strand conformation polymorphism (SSCP) analysis and DNA sequencing, we found that at least 17 suppressors are second-site intragenic revertants. The suppressors, like the original glp-1(ts) mutations, are all located in the cdc10/SWI6/ankyrin domain of GLP-1. cdc10/SWI6/ankyrin motifs have been shown to mediate specific protein-protein interactions in other polypeptides. We propose that the glp-1(ts) mutations disrupt contact between GLP-1 and an as yet unidentified target protein(s) and that the dominant suppressor mutations restore appropriate protein-protein interactions